amgen
amgen8d ago
New

Sr Machine Learning Engineer

Portugal - Lisbonsenior
Machine Learning EngineerData
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Quick Summary

Key Responsibilities

Engineer end-to-end ML pipelines—data ingestion, feature engineering, training, hyper-parameter optimization, evaluation, registration and automated promotion—using Kubeflow, SageMaker Pipelines,

Technical Tools
Machine Learning EngineerData
Information Systems

Responsibilities

~2 min read
  • Engineer end-to-end ML pipelines—data ingestion, feature engineering, training, hyper-parameter optimization, evaluation, registration and automated promotion—using Kubeflow, SageMaker Pipelines, Open AI SDK or equivalent MLOps stacks. 
  • Harden research code into production-grade micro-services, packaging models in Docker/Kubernetes and exposing secure REST, gRPC or event-driven APIs for consumption by downstream applications. 
  • Build and maintain full-stack AI applications by integrating model services with lightweight UI components, workflow engines or business-logic layers so insights reach users with sub-second latency. 
  • Optimize performance and cost at scale—selecting appropriate algorithms (gradient-boosted trees, transformers, time-series models, classical statistics), applying quantization/pruning, and tuning GPU/CPU auto-scaling policies to meet strict SLA targets. 
  • Instrument comprehensive observability—real-time metrics, distributed tracing, drift & bias detection and user-behavior analytics—enabling rapid diagnosis and continuous improvement of live models and applications. 
  • Embed security and responsible-AI controls (data encryption, access policies, lineage tracking, explainability and bias monitoring) in partnership with Security, Privacy and Compliance teams. 
  • Contribute reusable platform components—feature stores, model registries, experiment-tracking libraries—and evangelize best practices that raise engineering velocity across squads. 
  • Perform exploratory data analysis and feature ideation on complex, high-dimensional datasets to inform algorithm selection and ensure model robustness. 
  • Partner with data scientists to prototype and benchmark new algorithms, offering guidance on scalability trade-offs and production-readiness while co-owning model-performance KPIs. 

  • 3-5 years in AI/ML and enterprise software. 
  • Comprehensive command of machine-learning algorithmsregression, tree-based ensembles, clustering, dimensionality reduction, time-series models, deep-learning architectures (CNNs, RNNs, transformers) and modern LLM/RAG techniques—with the judgment to choose, tune and operationalize the right method for a given business problem. 
  • Proven track record selecting and integrating AI SaaS/PaaS offerings and building custom ML services at scale. 
  • Expert knowledge of GenAI tooling: vector databases, RAG pipelines, prompt-engineering DSLs and agent frameworks (e.g., LangChain, Semantic Kernel). 
  • Proficiency in Python and Java; containerization (Docker/K8s); cloud (AWS, Azure or GCP) and modern DevOps/MLOps (GitHub Actions, Bedrock/SageMaker Pipelines). 
  • Strong business-case skills—able to model TCO vs. NPV and present trade-offs to executives. 
  • Exceptional stakeholder management; can translate complex technical concepts into concise, outcome-oriented narratives. 

  • Experience in Biotechnology or pharma industry is a big plus 
  • Published thought-leadership or conference talks on enterprise GenAI adoption. 
  • Master’s degree in computer science and or Data Science  
  • Familiarity with Agile methodologies and Scaled Agile Framework (SAFe) for project delivery. 

  • Master’s degree with 8 + years of experience in Computer Science, IT or related field   

OR  

  • Bachelor’s degree with 10 + years of experience in Computer Science, IT or related field   
  • Certifications on GenAI/ML platforms (AWS AI, Azure AI Engineer, Google Cloud ML, etc.) are a plus. 

  • Excellent analytical and troubleshooting skills. 
  • Strong verbal and written communication skills 
  • Ability to work effectively with global, virtual teams 
  • High degree of initiative and self-motivation. 
  • Ability to manage multiple priorities successfully.  
  • Team-oriented, with a focus on achieving team goals. 
  • Ability to learn quickly, be organized and detail oriented. 
  • Strong presentation and public speaking skills. 

  

Objects in your future are closer than they appear. Join us.

CAREERS.AMGEN.COM

Amgen is an Equal Opportunity employer and will consider you without regard to your race, colour, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. 

We will ensure that individuals with disabilities are provided with reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.  

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51 065,45 EUR - 69 088,55 EUR

Location & Eligibility

Where is the job
Portugal - Lisbon
On-site at the office
Who can apply
Same as job location

Listing Details

Posted
August 6, 2026
First seen
August 14, 2026
Last seen
August 14, 2026

Posting Health

Days active
0
Repost count
0
Trust Level
28%
Scored at
August 14, 2026

Signal breakdown

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amgenSr Machine Learning Engineer