Scientist – Preclinical Team

United States·San DiegoFull-time (exempt)mid

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Capricor Therapeutics (NASDAQ: CAPR) is a biotechnology company dedicated to advancing transformative cell and exosome-based therapies for rare diseases.

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OtherScientist

Capricor Therapeutics (NASDAQ: CAPR) is a biotechnology company dedicated to advancing transformative cell and exosome-based therapies for rare diseases. At the forefront of our innovation is Deramiocel (CAP-1002), our lead cell therapy in late-stage development for Duchenne muscular dystrophy. We are also harnessing our proprietary StealthX™ exosome platform to unlock new possibilities in targeted delivery and vaccinology. Every program reflects our commitment to pushing the boundaries of science and delivering life-changing treatments to patients and families who need them most.

We are seeking a Scientist to join our Pre-Clinical team to support the progression of our therapeutic programs through the design, execution, and optimization of in vivo research activities and preclinical studies. This role requires deep expertise in in vivo methodologies, strong technical skills, and the ability to perform complex operations in a regulated environment.

Partner with the Principal Scientist and Director to provide preclinical expertise, including animal handling and study design.

Plan, execute, and analyze in vivo and ex vivo studies to support program objectives.

Perform cell-based assays and tissue analyses from in vivo studies; compile and report results.

Conduct survival surgeries and establish rodent models using aseptic techniques.

Develop, characterize, and implement new animal models to enhance pharmacology study effectiveness.

Maintain detailed, audit-ready documentation of all studies to ensure data integrity and traceability.

Optimize and implement best practices for in vivo research, including model selection, dosing strategies, and sample/data collection techniques.

Ensure compliance with regulatory guidelines and ethical standards for all preclinical activities.

Evaluate and integrate new technologies and platforms to improve study efficiency and quality.

Perform and interpret preclinical imaging studies (e.g., IVIS).

Contribute to a team culture that promotes continuous improvement, ownership, and inclusion.

Ph.D. in a relevant scientific discipline with expertise in nonclinical operations within drug discovery and development.

Hands-on experience with cell biology techniques, including RNA/DNA extraction, PCR, Western blot, ELISA, and interventional assays for small molecules and biologics.

Experience across diverse therapeutic modalities (small molecules, biologics, nucleic acid therapeutics, gene therapy).

Familiarity with age-related disease models (inflammation, metabolic disorders, neurodegeneration, muscle atrophy, bone/joint deficits).

Experience with metabolic chambers, behavioral assays, and related data analysis.

On-site laboratory environment with routine handling of animals and biological samples.

Prolonged periods of standing and performing surgical or technical procedures.

Ability to lift laboratory materials up to 20 pounds.

Why Capricor?

Capricor Therapeutics, a trailblazer in cell and exosome therapy, is dedicated to redefining standards of care with innovative treatments rooted in scientific excellence. Guided by integrity and a passion for patient-centered impact, our team is shaping a brighter future for healthcare. Join us and contribute to a mission-driven group that’s transforming lives with every breakthrough.

Come Work With Us!

At Capricor, you’ll thrive in a collaborative environment that nurtures your professional growth and innovation. Join a dedicated team fueled by a passion for advancing medical science and transforming patient lives through our cutting-edge therapies.

Please note that Capricor does not use Skype for interviews or recruiting activities. Candidates will only be contacted by an official Capricor email address which is @capricor.com. Additionally, Capricor will never ask potential employees to send a check or money to the Company for any reason.

Notice to Recruiting Agencies

Capricor Therapeutics does not accept candidate submissions or referrals from recruiting agencies, staffing firms, or third-party recruiters without expressed consent from Talent Acquisition management and a prior written agreement. Agencies that contact hiring managers directly, solicit business, or submit candidates without this approval will not be considered for any engagement. All such submissions become the property of Capricor Therapeutics, and no fees will be paid for any candidates hired as a result. We appreciate your cooperation and respect for this policy.