Bioinformatics Technologist I/II

Join Cleveland Clinic’s Main Campus where research and surgery are advanced, technology is leading-edge, patient care is world class and caregivers are family. Here, you will work alongside a passionate and dedicated team, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world.  

As a Bioinformatics Technologist I or II, you will develop, maintain and run software systems and bioinformatic pipelines for processing and analyzing next-generation sequencing data. In this role, you will perform software programming in various languages, including raw data quality control, sequence alignment, variant calling, annotation and reporting. You will provide input to develop software and data analysis solutions, complete department tasks and provide ongoing support for existing databases and software while working collaboratively with software engineers, computational biologists, and clinical and basic research scientists.

This role will participate in translational cancer research. The laboratory of Dr. Przybyl develops novel, clinically applicable liquid biopsy testing methods for sarcoma and applies multi-omic (genomic, transcriptomic, proteomic and methylome) high-throughput methods to discover new diagnostic markers and therapeutic targets in sarcomas. In this role, you will build bioinformatic pipelines, analyze high-throughput data and interpret results using statistical techniques. You will also develop and implement data analyses, acquire data from primary or secondary data sources and maintain databases.

• Bioinformatics Technologist

• Bioinformatics Technologist II

A caregiver who excels in this role will:  

• Assist with testing hypotheses and designing studies and recommending analytical strategies.

• Develop basic statistical, mathematical and predictive models, build algorithms and perform data analytics.

• In collaboration with bioinformatics specialists, maintain and run software systems for bioinformatics processing of sequence data, including raw data quality control, sequence alignment, variant calling, annotation and reporting.

• Develop and implement workflows for data analysis tools in collaboration with research scientists.

• Build and deploy data analysis support systems for large datasets, including well-structured flat files, APIs and other types of services.

• Acquire, clean, structure and manage data from multiple sources to ensure data quality.

• Utilize process enhancement opportunities to improve the efficiency of data pulling, reporting, programming and operations.

• Support existing production pipelines

• Troubleshoot and resolve issues as needed.

• Identify, evaluate and apply new computational methodologies and emerging technologies to improve existing methods and tools.

• Analyze genomics data in partnership with experimental and computational team members, industry partners and collaborators.

• Perform literature reviews to learn about gold standard data analysis methods.

• Write scripts, run analyses, visualize data and create figures for papers, presentations and posters.

• Solve problems related to data analysis and troubleshoot and adapt published methodologies.

• Prepare data for a variety of research projects.

• Assist lab members, including graduate students and postdoctoral fellows, with training on bioinformatic tools.

• Supervise and train trainees in their quantitative research projects.

• Contribute to research protocols and grant proposals.

• Perform other duties as assigned.

• Ability to perform work in a stationary position for extended periods.

• Ability to travel throughout the hospital system.

• Ability to operate a computer and other office equipment. 

• Ability to communicate and exchange accurate information.

• Follows standard precautions using personal protective equipment.

The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our caregivers and applicants for employment in our drug free environment. All offers of employment are followed by testing for controlled substances.

Cleveland Clinic Health System administers an influenza prevention program. You will be required to comply with this program, which will include obtaining an influenza vaccination on an annual basis or obtaining an approved exemption.

Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility. 

If applying for a Florida position, please see the following website for more information on the background screening requirements required by the Agency of Health Care Administration: https://info.flclearinghouse.com/

Please review the Equal Employment Opportunity poster. 

Cleveland Clinic is pleased to be an equal employment opportunity employer.