Clinical Trial Manager

We’re looking for an experienced, execution-focused Clinical Trial Manager to lead the day-to-day operational delivery of one or more of Character’s Dry AMD clinical trials. You will drive study execution from startup through close-out, manage vendor and site performance, and partner closely with Medical, Data, and Regulatory to keep your studies on time, on budget, and in compliance with GCP. Your work translates directly into Character’s mission: the studies you run generate the clinical evidence that will bring new therapies to patients with retinal disease.

This role is highly hands-on — you’ll be the person who knows the day-to-day status of your studies inside and out, anticipates risks before they surface, and keeps cross-functional partners and vendors aligned to a shared plan. This is a remote role reporting to Aggie Malloy (Head of Development Operations).

Study Execution & Delivery

• →Trial Management: Own day-to-day operational delivery of one or more clinical trials, driving timelines, quality, and issue resolution from startup through close-out
• →Study Planning: Develop and maintain study timelines, clinical plans, risk mitigation plans, and operational trackers, escalating issues before they affect delivery
• →Vendor & Site Oversight: Manage CROs, central labs, imaging vendors, and site performance, holding vendors accountable to scope, quality, and timelines
• →Enrollment & Monitoring: Track enrollment, monitoring visit completion, and data quality metrics, driving corrective action where needed

Compliance, Documentation & Cross-Functional Collaboration

• →GCP Compliance: Ensure studies are conducted in accordance with GCP, the protocol, and applicable regulations
• →Trial Master File: Maintain trial master file completeness and inspection readiness in partnership with study team members
• →Budget Management: Track study-level spend against budget, flagging variances and supporting invoice and payment review
• →Cross-Functional Partnership: Partner with relevant cross-functional stakeholders to keep study execution aligned with program strategy
• →Status Reporting: Provide clear, timely updates on study status, risks, and timelines to the program leadership

You bring strong command of clinical trial execution and are comfortable operating independently, owning a study or major workstream from startup through close-out. You anticipate problems before they become blockers, know how to hold vendors and sites accountable, and can flex between the details of day-to-day execution and the bigger picture of what a study needs to succeed.

You are organized, communicative, and thrive in a fast-moving, resource-lean environment where you’re trusted to run with your studies. You build strong working relationships with cross-functional partners and external vendors alike, and you bring the judgment to know when to escalate versus solve independently. Like us, you value integrity, individual accountability, team camaraderie, open communication, and a commitment to continuous learning and operational excellence.

Applicants must be authorized to work in the United States.