$210K–$260K/yr

Staff Software Engineer

United StatesUnited States·San Franciscolead
Software EngineerSoftware Engineering
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Quick Summary

Technical Tools
Software EngineerSoftware Engineering

Staff Software Engineer

Our client is a seed-stage healthcare/life-sciences company building AI agents that automate clinical trial workflows — attacking one of the biggest bottlenecks in drug development. Backed by $7M+ in funding, the platform is already used across 400+ research sites. This is a founding tech-lead role on a small, high-impact engineering team.

The role: A hands-on Staff Software Engineer (8+ yrs) to be the technical anchor of a small team — writing and reviewing code daily while mentoring three junior engineers and establishing engineering best practices, and partnering with product, customer success, and founders to ship zero-to-one AI-powered products.

Responsibilities

- Own and build AI-powered products end-to-end (agentic workflows, LLM features with production evals)

- Technical lead and mentor for three junior engineers; set best practices for code review and process

- Partner with CTO, PM, and customer success to shape zero-to-one products

- Architect and deliver full-stack apps across frontend, backend, infra, and data pipelines

Must-have

- Tech lead / technical anchor experience on an engineering team

- Full-stack product engineer who owns features end-to-end (backend-leaning generalists welcome)

- Mentor / bar-raiser able to establish engineering best practices

- 8–15 yrs full-stack product engineering, building AI/LLM features

- Zero-to-one, customer-facing product background (not deep infra)

- Recent (1–2 yrs) hands-on shipping of LLM features / AI agents in production

Nice-to-have

- Mix of startup (seed–Series B, founding/early hire) and larger-company experience

- CS degree or equivalent

- Production AI evals / LLM observability (LangSmith, Braintrust, W&B); multi-step agentic pipelines

- Genuine interest in bio, life sciences, or healthcare

Compensation & logistics

- Base salary: $210K–$260K, flexible for exceptional candidates

- Equity: 1–1.5%

- Full-time, hybrid: 3 days/week in-office (Mon, Tue, Thu), Financial District, San Francisco

- Visa: open to transfers (e.g., OPT, H-1B transfers); no new sponsorships

- Interview process: 3 steps — 30-min intro call, virtual system design interview, final on-site (technical + behavioral + team lunch)

Location & Eligibility

Where is the job
San Francisco, United States
On-site at the office
Who can apply
US

About this job

Pay per year
$210,000–$260,000 a year
20% above the $195,500 median for Software Engineer jobs on Jobera (5,727 salaries).
Who can apply
United States
Posted
30 days ago
Employer
has 257 open jobs on Jobera in 3 countries.

Listing Details

First seen
September 15, 2026
Last seen
October 16, 2026

Posting Health

Days active
30
Repost count
0
Trust Level
32%
Scored at
October 16, 2026

Signal breakdown

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Staff Software Engineer$210K–$260K