Process Engineering Associate I/II, Oncology

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

• →Apply sound engineering practices to scale, optimize, and improve molecular biology methods.
• →Conduct experiments to identify, isolate, and confirm root causes of process errors in our high-throughput molecular biology lab.
• →Develop methods to compile and analyze large amounts of process data to assess for process stability, trending, and areas for improvement.
• →Develop and implement software tools to aid in efficient sample processing within the clinical laboratory. 
• →Develop, implement, and use software tools to quantitatively analyze process efficiency and sources of error, to require moderate proficiency in R or Python.
• →Identify root causes for process and instrument errors and develop short term and long term solutions. 
• →Develop effective training plans for clinical personnel on modified/improved workflows.
• →Support transfer of new technology from Research and Development teams to the CLIA lab.
• →Generate proper documentation for all troubleshooting and qualification.

• Bachelor’s degree or equivalent degree in biology or clinical related sciences
• At least 6 months of experience with molecular biology techniques in a research or clinical laboratory
• Excellent attention to detail
• Effective written and verbal communication skills
• Possess logical troubleshooting skills
• Previous automation or clinical laboratory experience is preferred

• Start-up experience
• Experience with next-generation sequencing (NGS)
• Knowledge of molecular oncology
• Experience in a cell-free DNA setting

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com