Office Manager

• Join a world-class team of scientists, researchers, and entrepreneurs building the future of drug discovery.

• Partner with leadership to shape how a fast-growing company operates day-to-day.

• Build and scale foundational office systems, processes, and culture in a high-growth environment.

• Operate with trust, ownership, and transparency in a mission-driven company advancing science.

Achira is seeking a highly organized, proactive, technically savvy, and detail-oriented Office Manager to oversee the daily operations of our San Francisco office. Reporting to the Senior Executive Assistant, you will play a critical role in ensuring the workplace runs smoothly, efficiently, and professionally.

You’ll be the backbone of the office—managing logistics, vendor relationships, and employee experience—while supporting broader operational initiatives led by the leadership team. This role is ideal for someone who thrives in fast-paced startup environments and enjoys building structure from the ground up.

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  Own office operations: manage day-to-day office logistics, including supplies, equipment, layout, and maintenance to ensure a seamless workplace experience.

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  Coordinate vendors and facilities: oversee relationships with building management, IT support, cleaning services, and other vendors; manage contracts and service quality.

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  Support employee experience: help onboard new hires, maintain a welcoming office environment, and support in-office culture and engagement initiatives.

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  Partner with the Senior Executive Assistant and administrative team: assist with operational priorities, internal coordination, and execution of company-wide initiatives.

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  Manage office budget and expenses: track spending, process invoices, and ensure cost-effective operations.

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  Plan and execute events: organize internal gatherings that strengthen team culture.

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  Ensure operational readiness: anticipate needs, troubleshoot issues quickly, and continuously improve office systems and workflows.

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  Act as the lead in-office presence: maintain a consistent onsite presence to support the team, visitors, and daily operations—this role is built around being physically present and accessible.

• 3+ years of experience in office management, workplace operations, or similar roles, ideally in a startup or high-growth environment.

• Highly organized and detail-oriented, with the ability to manage multiple priorities and keep operations running smoothly.

• Strong problem-solver who is proactive, resourceful, and able to act independently.

• Excellent interpersonal skills; you create a positive, welcoming environment and communicate effectively across teams.

• Comfortable with basic tools (Google Workspace, Slack, Notion, etc.) and not afraid to pick up new ones quickly.

• Hands-on and adaptable — excited to roll up your sleeves and build processes in a fast-paced, evolving environment.

• Mission-driven and motivated to support a team advancing drug discovery.